Monday, August 8, 2016

New carbon nanomaterial pot several times deeper than any similar nanostructure

A novel, pot-shaped, carbon nanomaterial developed by researchers from Kumamoto University, Japan is several times deeper than any hollow carbon nanostructure previously produced. This unique characteristic enables the material to gradually release substances contained within and is expected to be beneficial in applications such as drug delivery systems.

Carbon is an element that is light, abundant, has a strong binding force, and eco-friendly. The range of carbon-based materials is expected to become more widespread in the eco-friendly society of the future. Recently, nanosized (one-billionth of a meter) carbon materials have been developed with lengths, widths, or heights below 100 nm. These materials take extreme forms such as tiny grained substances, thin sheet-like substances, and slim fibrous substances. Example of these new materials are fullerenes, which are hollow cage-like carbon molecules; carbon nanotubes, cylindrical nanostructures of carbon molecules; and graphene, one-atom thick sheets of carbon molecules.

Why are these tiny substances needed? One reason is that reactions with other materials can be much larger if a substance has an increased surface area. When using nanomaterials in place of existing materials, it is possible to significantly change surface area without changing weight and volume, thereby improving both size and performance. The development of carbon nanomaterials has provided novel nanostructured materials with shapes and characteristics that surpass existing materials.

Now, research from the laboratory of Kumamoto University's Associate Prof. Yokoi has resulted in the successful development of a container-type carbon nanomaterial with a much deeper orifice than that found in similar materials. To create the new material, researchers used their own, newly developed method of material synthesis. The container-shaped nanomaterial has a complex form consisting of varied layers of stacked graphene at the bottom, the body, and the neck areas of the container, and the graphene edges along the outer surface of the body were found to be very dense. Due to these innovate features, Associate Prof. Yokoi and colleagues named the material the "carbon nanopot."

Tuesday, July 19, 2016

New research delves into physical properties of nanoparticles for successful drug delivery

Nanoparticles are being studied as drug delivery systems to treat a wide variety of diseases. New research delves into the physical properties of nanoparticles that are important for successfully delivering therapeutics within the body, with a primary focus on size. This is especially important as relatively subtle differences in size can affect cell uptake and determine the fate of nanoparticles once within cells.
By exploring various strategies for fabricating nanoparticles, the investigators provide valuable information for generating uniform nanoparticles in high yields that will be efficiently taken up by target cells.

Monday, April 18, 2016

Scientists develop graphene-based sensor that can detect harmful air pollution in home

Scientists develop graphene-based sensor that can detect harmful air pollution in home: Scientists from the University of Southampton, in partnership with the Japan Advanced Institute of Science and Technology, have developed a graphene-based sensor and switch that can detect harmful air pollution in the home with very low power consumption.

Monday, April 11, 2016

Novel nanoparticle drug delivery system for enhanced tumor penetration of cancer drugs

Novel nanoparticle drug delivery system for enhanced tumor penetration of cancer drugs: For more than a decade, biomedical researchers have been looking for better ways to deliver cancer-killing medication directly to tumors in the body. Tiny capsules, called nanoparticles, are now being used to transport chemotherapy medicine through the bloodstream, to the doorstep of cancerous tumors.

Saturday, April 11, 2015

Plaque-busting nanoparticles could help fight tooth decay

Nanoparticles carry the antibacterial drug farnesol to the surface of the teeth, where they release their payload when triggered by acidic environments.

Nanotechnology might soon save you a trip to the dentist. Researchers have developed tiny sphere-shaped particles that ferry a payload of bacteria-slaying drugs to the surface of the teeth, where they fight plaque and tooth decay on the spot. The approach could also be adapted to combat other plaquelike substances, known as biofilms, such as those that form on medical devices like orthopedic implants.
"It's quite clever," says oral microbiologist Robert Allaker of Queen Mary University of London, who was not involved with the research. "I think it was an innovative piece of work."
Plaque is a film made up of bacteria and a matrix of polymers composed of linked sugars, which clings tenaciously to teeth. When bacteria digest sugars in the mouth, they produce acid as a byproduct, which eats away at teeth, eventually causing decay. Topical antibacterial drugs don’t work well on plaque because saliva quickly washes them away.

Nanoparticles can solve this problem by clinging to the surface of teeth and carrying drugs along with them. Although this is not the first technique to employ such a strategy, the research improves upon previous methods, because these particles attach not only to the tooth, but also to the plaque biofilm.

Friday, April 10, 2015

Engineers now understand how complex carbon nanostructures form

CNTs are much smaller than the width of a human hair and naturally form "forests" when they are created in large numbers. These forests, held together by a nanoscale adhesive force known as the van der Waals force, are categorized based on their rigidity or how they are aligned. For example, if CNTs are dense and well aligned, the material tends to be more rigid and can be useful for electrical and mechanical applications. If CNTs are disorganized, they tend to be softer and have entirely different sets of properties.

"Scientists are still learning how carbon nanotube arrays form," said Matt Maschmann, assistant professor of mechanical and aerospace engineering in the College of Engineering at MU. "As they grow in relatively dense populations, mechanical forces combine them into vertically oriented assemblies known as forests or arrays. The complex structures they form help dictate the properties the CNT forests possess. We're working to identify the mechanisms behind how those forests form, how to control their formation and thus dictate future uses for CNTs."
Currently, most models that examine CNT forests analyze what happens when you compress them or test their thermal or conductivity properties after they've formed. However, these models do not take into account the process by which that particular forest was created and struggle to capture realistic CNT forest structure.


Monday, March 30, 2015

Carbon nanotube fibers make superior links to brain






Carbon nanotube fibers invented at Rice University may provide the best way to communicate directly with the brain.
The fibers have proven superior to metal electrodes for deep brain stimulation and to read signals from a neuronal network. Because they provide a two-way connection, they show promise for treating patients with neurological disorders while monitoring the real-time response of neural circuits in areas that control movement, mood and bodily functions.
New experiments at Rice demonstrated the biocompatible fibers are ideal candidates for small, safe electrodes that interact with the brain's neuronal system, according to the researchers. They could replace much larger electrodes currently used in devices for deep brain stimulation therapies in Parkinson's disease patients.
They may also advance technologies to restore sensory or motor functions and brain-machine interfaces as well as deep brain stimulation therapies for other neurological disorders, including dystonia and depression, the researchers wrote.
The paper appeared online this week in the American Chemical Society journal ACS Nano.
The fibers created by the Rice lab of chemist and chemical engineer Matteo Pasquali consist of bundles of long nanotubes originally intended for aerospace applications where strength, weight and conductivity are paramount.
The individual nanotubes measure only a few nanometers across, but when millions are bundled in a process called wet spinning, they become thread-like fibers about a quarter the width of a human hair.
"We developed these fibers as high-strength, high-conductivity materials," Pasquali said. "Yet, once we had them in our hand, we realized that they had an unexpected property: They are really soft, much like a thread of silk. Their unique combination of strength, conductivity and softness makes them ideal for interfacing with the electrical function of the human body."